Browsing by Author "Aboyeji, A. P."

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Asymtomatic bacteriuria in antenatal patients in Ilorin, NIgeria
(Oman Medical Specialty Board, 2012) Ajayi, A. B.; Nwabuisi, C,; Aboyeji, A. P.; Ajayi, N. S.; Fowotade, A.; Fakeye, O. O.
Objective: To determine the prevalence of asymptomatic bacteriuria, bacteriology and sensitivity pattern in Ilorin using the gold standard of urine culture. Methods: A prospective study was carried out from 1st July to 31st October 2007, at the University of Ilorin Teaching Hospital (UITH) on 125 consenting asymptomatic pregnant women. A structured proforma was used to collect information from the women and a midstream urine specimen collected for bacteriological culture. Results: Of the 125 pregnant women, 50 had bacteriuria on urine culture giving a prevalence of 40%. The mean age of the women was 28.5 years with a standard deviation of 4.95. The age ranged between 14 and 40 years. Staphylococcus aureus was the commonest pathogen isolated (72%), followed by Proteus spp (14%). Most of the organisms showed good sensitivity to Nitrofurantoin and gentamicin. Conclusion: The prevalence of asymptomatic bacteriuria in Ilorin is high and routine urine culture is advocated for all pregnant women at booking.
Management and the prevention of anaemia in pregnancy
(Tropical Journal of Obstetrics and Gynaecology (TJOG), 2023) Afolabi, B. B.; Ogunbode, O. O.; Ezechi, O. C.; Ogu, R. N; Agboghoroma, C. O; Aboyeji, A. P.; Tukur, J; Oyebode, T; Daru, P. H.; Oluwole. A. A.; Onyebuchi, A.; Audu, B.; Aimakhu, C.O.; Akinola, O. I; Ikpeze, O. C.; Sadauki, H. M
Anaemia during pregnancy is a significant public health concern in this country. With 40% of the population living in poverty and 63% facing multidimensional poverty as reported by the National MPI 2022, it is not surprising that women often have poor diets, making them more prone to iron and folate deficiency anaemia, which are the leading causes of anaemia during pregnancy. Other factors contributing to anaemia during pregnancy include having multiple pregnancies in quick succession, giving birth to multiple babies, pre-pregnancy menorrhagia, worm infestation, severe and prolonged hyperemesis gravidarum, among others. Anaemia during pregnancy can cause serious complications for the fetus, such as preterm birth and low birth weight. It can also affect the mother's well-being, with severe anaemia increasing the risk of death or near misses. Recent evidence also suggests that anaemia during pregnancy significantly increases the risk of postpartum haemorrhage caused by uterine atony. It's crucial for healthcare providers to be aware of the issues associated with anaemia during pregnancy and the measures for preventing and detecting high-risk pregnancies early. Healthcare providers must understand the different types of anaemia, common symptoms, and treatment options to recognize the warning signs of anaemia and avoid complications. This clinical guideline is designed for obstetricians and midwives to help manage pregnant women with anaemia appropriately. The document's layout and practical step-by-step approach to managing anaemia during pregnancy are commendable, and the team of experts who produced this high-quality document under the chairmanship of Prof Abiodun Aboyeji deserves appreciation. All members of the committee deserve commendation for a job well done. Healthcare practitioners should use this guideline to manage anaemia during pregnancy effectively, reducing complications for both mother and foetus, and ultimately reducing the burden of high maternal and perinatal mortality and morbidity related to anaemia. This is one of four clinical guidelines to be produced by the SOGON Executive under my leadership. The other three will be rolled out shortly.
Reliability of urine multistix and Gram stain in the detection of asymptomatic Bacteriuria in pregnancy
(West African College of Physicians and West African College of Surgeons, 2010) Ajayi, A. B.; Nwabuisi, C,; Aboyeji, A. P.; Fowotade, A.; Fakeye, O. O.
BACKGROUND: Urinary tract infection is a common problem during pregnancy. Asymptomatic bacteriuria can cause the development of serious complications affecting both the mother and foetus. Urine culture, the traditional screening test is relatively expensive, time consuming and requires a microbiology laboratory and trained staff. However simpler, less expensive tests which include urine multistix and urine gramstain better suited for developing countries are available. OBJECTIVE: To determine the sensitivity, specificity and predictive values of multistix nitrite, leucocyte esterase (LE) and urine gram staining for asymptomatic bacteriuria in pregnancy. METHODS: A cross-sectional study was carried out from 1st July to 31st October 2007, at the University of Ilorin Teaching Hospital (UITH) on 125 consenting asymptomatic pregnant women. A structured proforma was used to collect information from the women and a midstream urine specimen collected in two sterile bottles. One was tested with Multistix for the presence of nitrite and leucocyte esterase and the other for bacteriological culture and urine gram stain. RESULTS: Using the gold standard of urine culture, the sensitivities of Multistix nitrite and leucocyte esterase were each 14% and the specificity 100% and 96% respectively. Urine gram stain had a sensitivity of 98% and a specificity of 74.7%. CONCLUSION: Multistix"" nitrite and leucocyte esterase are not sufficiently sensitive to be used as a screening tool for asymptomatic bacteriuria. Urine gram stain can be used in areas where facilities are inadequate for culture but cannot replace it. More studies are required to determine the accuracy of urine gram-stain.