Browsing by Author "Adebowale, A."

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Epidemiology of rubella disease in south-west Nigeria: trends and projection from measles case-based surveillance data
(AOSIS, 2014) Fatiregun, A.; Fagbamigbe, A. F.; Adebowale, A.
Although surveillance for rubella does not exist in Nigeria, a measles case-based surveillance system was introduced in 2005 as one of the strategies for measles morbidity control, and included laboratory testing for confirmation of the disease. In this report, we provide the epidemiological distribution of rubella-confirmed cases reported from the south-west zone of the country, and predict the expected number of cases in the ensuing years. A descriptive analysis was carried out of rubella cases reported in the measles case-based surveillance data from the south-west zone of Nigeria for the period 2007-2012. Using an additive time series model, we predicted the expected number of cases until the year 2015. Four hundred and thirty-eight (5.4%) rubella cases were confirmed from 8 046 suspected measles cases. Cases were confirmed from all six states within the zone. The majority (87.3%) were individuals < 15 years of age and 40.9% were female. Seasonal variation existed, with peaks of infection in the first and third triannual periods of the year, while annual trends showed peaks in 2007 and 2010. Based on projections, there was a reduction in the number of expected cases. Rubella testing, in parallel with measles case-based surveillance, provides understanding of the epidemiology of rubella infection in south-west Nigeria.
The current status of kidney transplantation in Nigerian children: still awaiting light at the end of the tunnel
(Pediatric Nephrology, 2020) Eke, F. U.; Ladapo, T. A.; Okpere, A. N.; Olatise, O.; Anochie, I.; Uchenwa, T.; Okafor, H.; Ibitoye, P.; Ononiwu, U.; Adebowale, A.; Akuse, R.; Oniyangi, S.
Background Kidney transplantation (KT) is the gold standard treatment for childrenwith chronic kidney disease stage 5 (CKD5). It is easily accessible in well-resourced countries, but not in low/middle-income countries (LMICs). We present, a multicenter experience of paediatric KT of children domiciled in Nigeria. We aim to highlight the challenges and ethical dilemmas that children, their parents or guardians and health care staff face on a daily basis. Methods A multicentre survey of Nigerian children who received KTs within or outside Nigeria from 1986 to 2019 was undertaken using a questionnaire emailed to all paediatric and adult consultants who are responsible for the care of children with kidney diseases in Nigeria. Demographic data, causes of CKD5, sources of funding, donor organs and graft and patient outcome were analysed. Using Kaplan-Meier survival analysis, we compared graft and patient survival. Results Twenty-two children, aged 4–18 years, received 23 KTs, of which 12 were performed in Nigeria. The male-to-female ratio was 3.4:1. Duration of pre-transplant haemodialysis was 4–48 months (median 7 months). Sixteen KTs were self-funded. State governments funded 3 philanthropists 4 KTs. Overall differences in graft and patient survival between the two groups, log rank test P = 0.68 and 0.40, respectively were not statistically significant. Conclusions The transplant access rate for Nigerian children is dismal at < 0.2%. Poor funding is a major challenge. There is an urgent need for the federal government to fund health care and particularly KTs