Browsing by Author "Adedokun, R. A. M."

Now showing 1 - 8 of 8

A case report of Management of impaction colic in Donkey in Ibadan, Nigeria
(Faculty of Veterinary Medicine, University of Ibadan, Nigeria, 2020) Adedokun, R. A. M.; Olaifa, A. K.; Alaba, B. K.; Olaogun, S. C.
A 13 year old male donkey (jack), weighing 171 kg was presented with history' of frequent prolonged recumbency and eliciting sand bath action. The donkey was dehydrated, anorexic, inactive, refused to drink and no defecation. Rolling, bloating, uneasiness, distress were also observed, grunting sound was also heard whenever the animal attempted to rise from recumbency. Rectal temperature was 36.6°C, pulse and respiratory rates were 60 and 30 per minute, respectively. Mucous membrane initially appeared normal but later became congested with generalised bruises on the body of the donkey especially at the bony prominences. Colic was clinically diagnosed and treatment immediately instituted. Animal was drenched with 1 litre of liquid paraffin; 2 litres of lactated Ringer’s solution was given intravenously, I/V; lntramuscular(l/M) injections of 8 mis (2.25mg/Kg) of vitamin B complex and 3.8 mis of50mg/ml (1.1 mg/Kg) Flunixin Meglumine were also administered. The patient was treated for five consecutive days with significant improvement on the third day. The rolling, bloating, distress and uneasiness were relieved after day four of treatment and the donkey was discharged on the fifth day. This report highlighted the causes, type and nature of this particular case, management procedures and preventives strategy of colic in donkey.
A case report of management of pasture bloat in a post-parturient West African Dwarf Ewe in Ibadan, Nigeria
(Faculty of Veterinary Medicine, University of Ibadan, Nigeria, 2020) Olaogun, S. C.; Adedokun, R. A. M.
Black anterior and white posterior body coat was presented at the Veterinary Teaching Hospital, University of Ibadan, with complaints of abdominal distension, sudden laboured breathing and anorexia. The animal was said to have lambed 7 days earlier and was fed with cassava peels and grasses. On clinical examination, the eye ball appeared bulged and starry; the stomach was hard on palpation with frothy buccal exudate and persistent grinding of teeth. The heart rate was 68/minute, respiratory rate was 15/minute and rectal temperature was 39.8oC. Bloat was clinically diagnosed. With the patient properly restrained, an improvised stomach tube was rinsed in vegetable oil and slowly inserted through the oesophagus into the rumen and the gas eructated. Liquid paraffin (15 mls) was subsequently introduced into the rumen via the tube. On removing the stomach tube, a long strand of fresh undigested pasture came out with the tube from the gastrointestinal tract. The hard stomach was thereafter relieved within 5 minutes of the procedure. Long acting Oxytetracycline hydrochloride (2 mls) and 1ml Diclofenac were administered (intramuscularly) simultaneously at different injection sites. Plenty of water was advised to be given orally after 30minutes. Complication resolved and complete recovery of the ewe was achieved after 5 consecutive days of treatment.
A case of eperythrozoonosis in royal python (Python requis) in zoological garden in Ibadan, Nigeria
(Sokoto Journal of Veterinary Sciences, 2010-12) Sonibare, A. O.; Kumshe, H. A; Adejinmi, J. O.; Ajuwape, A. T. P.; Adedokun, O. A.; Adedokun, R. A. M.; Ayoade, G.O.; Akinboye, G.B.
Eperythrozoonosis in Royal python reported. Clinical observations included dullness, paleness and jaundiced mucous membrane. Parasitological examination revealed rickettsiae, Eperythrozoon. Stressful condition associated with Royal python in captivity resulted in lower immunity and development of evident infection. Routine screening of Royal Python's prey to prevent transfer of ticks by contact is advocated.
Concurent fatal helm1nthosis and balantidos1s in red monkey (Erythrocebuspatas) in Ibadan, Nigeria
(Nigerian Veterinary Journal, 2002) Adedokun, O. A.; Adedokun, R. A. M.; Emikpe, B. O.; Ohore, O. G.; Oluwayelu, D.O; Ajayi, O.L.
Fresh fecal specimen from a moribund red monkey (Erythrocebuspatas) from the zoological garden, University of Ibadan with a history of dysentery was examined. Ova of Triclmris spp., Enterobius spp, Ancylostoma spp. and Strongyloides spp., as well as Balantidium spp oocysts were found. Post mortem, findings revealed the large intestine heavily infected with worms especially Trichuris spp., Ancylostoma spp. and Trichostronglus spp. which were enmeshed in a thick layer of mucous and blood on the mucosa. The public health importance is discussed.
Evaluation of amoxicillin content in commonly used multisource Injectable brands in veterinary practice
(Egypt’s Presidential Specialized Council for Education and Scientific Research, 2019) Gberindyer, A .F.; Olaogun, S. C.; Omotosho, O. O.; Adedokun, R. A. M.; Shima, F. K.
THE AIM Is To Evaluate Amount Of Amoxicillin In The Array Of Its Injectable Formulations From Multisource Marketed And Commonly Used In Veterinary Practice In Nigeria. The Amount Of Amoxicillin In Each Of The 10 Brands Sampled Was Analysed Using A High-Performance Liquid Chromatography. Thereafter, Percentages Of The Labelled Amount Of Amoxicillin Were Determined And Compared With 90-120% Specified In USP And IP. Samples G, H, And J Contained 93%, 98%, And 108%, Respectively Of The Labeled Amount Of Amoxicillin, While B, C, And A Contained Only 39%, 56%, And 58%, Respectively. Again, Samples I, F, D, And E Contained 124%, 135%, 147%, And 413%, Respectively Of The Labelled Amount. Thus, Only Brands G, H, And J Passed Assay Quality Test (AQT) Since The Amount Of Amoxicillin They Contained Was Within The Specified USP And IP Range, And Are Considered Pharmaceutically Equivalent, Consequently, Interchangeable For Intravenous Administrations. Whereas, Brands A, B, And C Failed AQT Because They Contained Less Than The Amount Of Amoxicillin Required, So Even When Used Prudently There Could Be Therapeutic Failure, Bacterial Resistance, And Public Health Implications. Similarly, Brands D, E, F, And I Could Cause Toxicity And High Tissue Residues Because They Contained Higher Than The Required And Labelled Amount Of Amoxicillin. About 30% And 40% Of The Analysed Amoxicillin Brands Contained Less And More Than The Required Amount Of Amoxicillin, Respectively. However, 30% Contained The Amount Within The Specified Range. Consequently, There Is High Rate Of Substandard Amoxicillin Injectable Brands For Veterinary Use In Nigeria Hence The Need For Regular Monitoring.
Prevalence of Pseudomonas Species, Escherichia coli and Staphylococcus aureus in milk samples of apparently normal lactating cows at various cattle farms in Ibadan, Nigeria
(Faculty of Veterinary Medicine, Alexandria University in Egypt, 2023) Amosun, E. A.; Adedokun, R. A. M.; Banwo, O. G.; Akhaine, S.; Amoo, O.; Jeremiah, O. T.
This study was aimed at identifying the most significant bacteria isolates in the udder quarters as pathogenic causes of subclinical mastitis, and as well to investigate antibiotic sensitivity of the isolated organisms. The study was carried out at three cattle farm locations in Ibadan metropolis, Oyo State, Nigeria. A total number of 105 apparently healthy lactating cows without udder inflammation were sampled for milk; sampling by hand stripping was done after swabbing the teats with cotton wool dipped in alcohol and discarding the first stripping. Culture and isolation techniques, as well as biochemical tests of milk samples from the four quarters of udders of the 105 apparently healthy cows were carried out. In addition, an in vitro antibacterial sensitivity test was performed for six classes of antibacterial agents. A test of independent assessment (Chi-square test) was used to determine if association existed between the bacterial species collectively isolated and the affected animals (p = 0.716) or quarters (p = <0.000). The study established the presence of subclinical mastitis associated with known pathogens of which Pseudomonas species (67.9%), Staphylococcus aureus (53.6%) and Escherichia coli (14.3%) were most significant in decreasing order of quarter distribution in average percentages. The study further revealed differences in susceptibility of the various quarters and spread of infection. The isolated pathogens were generally most susceptible to the fluoroquinolones while varying degrees of resistance was a finding for other classes of antibacterial used possibly due to their prolonged and indiscriminate use; and this calls for caution by animal health care providers.
Socio-demographic structure and constraints of Smallholder Dairy farmers in Oyo state, Nigeria
(Integrity Research Journals, 2019) Abiola, J. O.; Olaogun, S. C.; Adedokun, R. A. M.; Onaro, S. K.
The contribution of dairy farming to the socio-economic development of Oyo state and Nigeria at large cannot be underestimated; we therefore sought to establish socio-demographic status and constraints of small holder dairy farmers at five milk collection centres built by FC WAMCO in Oyo state, Nigeria. Well structure close ended question-based questionnaires were administered in the study location. Farmer’s demography revealed 63.64% and 36.36% male and female respectively, majority (46.54%) were between 30 and 40yrs. 73.82% do not have formal education, 40.18% reported 10 years of rearing. Major constraints identified were; lack of milking equipment reported by 97.64%, 93.82% reported lack of milk preservation facilities. 97.64% reported high cost of breeder stock. 51.82% were not aware of artificial insemination. Inaccessibility to good water was reported by 98.55%, 93.09% reported cattle rustling, 70% were not aware of any biosecurity measures.
Toxicological studies of ethanol leaf extract of cassia fistula on haematological and biochemical parameters of Wistar albino rats
(Academic Journals, Nigeria, 2019) Adedokun, R. A. M.; Azeez, O. I.; Adeoye, A. O.; Olaogun, S. C.; Oladavies, E. O.
Aim: Cassia fistula L. (Fabaceae) is an annual herbaceous plant used in folklore medicine for the treatment of a wide range of conditions such as astringent, febrifuge and purgative. But the effects have not been well elucidated. This study was aimed at investigating the effect of Cassia fistula on haematological and serum biochemical indices in Wistar rats. Materials and Methods: Phytochemical constituents from the ethanol extract of C. fistula were identified by qualitative techniques and gas chromatography-mass spectroscopy (GC-MS). Twenty male Wistar rats were randomly assigned into four groups of five rats each. Group A, the control, received 0.2ml of corn oil each daily for 7 days; Group B rats were given 100mg/kg b.w. of Cassia fistula extract, Group C were given 200mg/kg b.w. of the extract while the rats in Group D were given 300mg/kg b.w ethanol extract of Cassia fistula orally for 7 days. Blood samples were collected afterward for determination of haematological parameter while plasma biochemistry was carried on the plasma after 7 days of treatment with the extract. Frequency of micronucleated polychromatic erythrocytes was also determined from blood Giemsa stained smear. Results: Qualitative analyses revealed the presence of tannins, saponins, alkaloids, anthraquinones, cardenolides, and phenols. In GC-MS analysis, 19 compounds including phytol, oleic, myristic acids etc. were detected from the ethanol leaf extract of C fistula. Oral treatment of Cassia fistula was found to be safe up to the 300mg/kg b.w dose because haematological and biochemical parameters in treated rats were comparable to the untreated control. In fact, the extract showed nephroprotective and hepatoprotective activity at 200 mg/kg. Conclusion: This study showed that ethanol leaf extract of Cassia fistula is not toxic upt to 300 mg/kg b.w, instead the extract showed some protective effects on liver and kidney functions at the 200 mg/kg b.w dose. This dosage should therefore be explored further for therapeutic purposes.