Browsing by Author "Morenikeji, O."

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A cross-sectional study on urogenital schistosomiasis in children; haematuria and proteinuria as diagnostic indicators in an endemic rural area of Nigeria
(Faculty of Medicine, Makerere University, 2014-06) Morenikeji, O.; Qazim, J.; Omoregie, C.; Hassan, A.; Nwuba, R.; Anumudu, C.; Adejuwon, S.; Salawu, O.; Jegede, A.; Odaibo, A.
Background: Rapid and accurate diagnosis is necessary for the management of schistosomiasis in endemic areas. Objective: To assess the burden of urogenital schistosomiasis and the diagnostic efficiency of morbidity indicators of the disease in an endemic rural community of Nigeria. Methods: A cross-sectional school-based study was conducted. Urine samples of 487 pupils were screened microscopically for S. haematobium and tested for haematuria and proteinuria using chemical reagent strips. Results: The prevalence and intensity of infection were 57.1% and 45.0 eggs/10 mL urine respectively. Prevalence of infection in male (54.1%) and female (60.3%) individuals showed no significant variation (P>0.05). However, prevalence of infection was age dependent with those in age groups 3-5 and 12-14 years having the least and highest prevalence of infection respectively (P<0.05). Microhaematuria and proteinuria varied significantly with ages of the pupils with least (14.0, 40.0%) and highest (60.0, 80.0%) prevalence recorded in age groups 3-5 and 15-19 years respectively (P<0.05). Proteinuria showed higher sensitivity (80.3%) compared to microhaematuria (73.3%). Conclusion: Schistosomiasis is highly endemic in the study area and the use of microhaematuria and proteinuria for mapping the infected population prior treatment could be adopted.
Electrocardiographic study of rescued white-bellied pangolins (Phataginus tricuspis) immobilized with xylazine combination.
(African Association of Biomedical Scientists / Ibadan Biomedical Communications Group, 2024) Adejumobi, O. A.; Fawole, O.; Omotosho, O. O.; Hamzat, A. A.; Olakojo, T. A.; Ofua, M.; Wirtu, G.; Oyagbemi, A. A.; Omobowale, T. O.; Morenikeji, O.
Optimal health is required in endangered species and one of the vital organs to assess the overall health of an animal is the heart. The Electrocardiograph (ECG) provides information on the health status of the heart. There is dearth of information on the electrocardiographic parameters of white bellied pangolins. In this study, we obtained cardiac parameters from clinically healthy white-bellied pangolins (n=26) rescued from trade in Southwestern Nigeria. The Pangolins were sedated with Ketamine hydrochloride (10mg/kg) and Xylazine (3mg/kg). Electrocardiography was recorded with the animal on dorsal recumbence using a 6/7 lead computer ECG machine. Standard bipolar (I, II, III) and augmented unipolar (aVR, aVL and aVF) leads readings were recorded. Measurements are presented as mean±standard deviation. Electrocardiogram (ECG) readings were analysed using Descriptive statistics, Student t-test at 5% level of significance. Electrocardiographic parameters such as heart rate (HR), P-wave duration, PR-interval, QRS duration, QT interval, QTc interval and Ra were recorded for each of the leads. The HR ranged from 54 to 109 beats/min with a mean ± standard deviation of 82.85±13.50 beats/min. Lead II recordings showed a P-wave duration of 61.19±16.73 ms, PR interval 94.88±18.88 ms, QRS duration 50.77±16.05 ms, QT interval 299.88±31.23 ms, QTc interval 347.88±37.07 ms and Ra 1.28±0.38 mV. There were no significant differences in the ECG parameters between male and female white-bellied pangolins in all the leads measured. The findings of this study should provide clinical reference for healthy management of African pangolins. It would also serve as a reference values for further research.
Management of Epitheliogenesis Imperfecta in A Piglet (Sus Scrofa Domesticus) in Ibadan, Nigeria
(Nigerian Veterinary Medical Association (NVMA), 2016) Ogunro, B. N.; Otuh, P. I.; Olatunji-Akioye, A.; Emikpe, B. O.; Oyebanji, V.; Adejumobi, O. A.; Morenikeji, O.
Urine turbidity and microhaematuria as rapid assessment indicators for schistosoma haematobium infection among school children in endemic Areas
(Science Publications, 2012) Hassan, A.; Ntiaidem, U.; Morenikeji, O.; Nwuba, R.; Anumudu, C.; Adejuwon, S.; Salawu, O.; Jegede, A.; Odaibo, A.
Problem statement: Urinary schistosomiasis is highly endemic in Nigeria and for effective control measure, an efficient, quick and yet cheap diagnosis should be integrated. This will ensure the proper management of infection due to Schistosoma haematobium in low resource communities of Nigeria. Approach: This cross-sectional study recruited a total of 456 (252 males, 204 females) school children aged 3-20 years between November 2010 and June 2011. Urine samples were examined macroscopically for turbidity and subsequently screened for microhaematuria using diagnostic reagent strips. The microscopic examination of urine samples for schistosome eggs was used as the standard for diagnosis. Results: The prevalence of S. haematobium and geometric mean intensity of infection were 54.8% and 13.9 ± 0.67 eggs/10 mL of urine respectively. The age and sex prevalence of urinary schistosomiasis showed no significant differences (p>0.05). The prevalences of urine turbidity and microhaematuria were 37.1 and 53.9% respectively and these varied significantly across age groups (p<0.05). The sensitivities of urine turbidity and microhaematuria used for the indirect diagnosis of urinary schistosomiasis were 54.8 and 59.3 (p>0.05) with their corresponding specificities 80.2 and 65.8% respectively. Intensity of infection was significantly correlated with the indirect diagnostic methods, urine turbidity (r = 0.203, p<0.01) and microhaematuria (r = 0.487, p<0.01). Conclusion: The possible use of urine turbidity as an indicator for rapid diagnosis of urinary schistosomiasis in low resource communities is implied.