Browsing by Author "Oluwasola, T. O."

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    Candida species causing vulvovaginitis among patients in Babcock University Teaching Hospital, Ilishan-Remo, Ogun State: A retrospective cross-sectional study.
    (2024) Ajani, T. A.; Elikwu, C. J.; Tuta, K. E.; Shonekan, O. A.; Okangba, C. C.; Anaedobe, C. G.; Ebeigbe, E.; Osinowo, A. O.; Makanjuola, O. B.; Ogunbiyi, A. I.; Sadare, O. A.; Oluwasola, T. O.; Nwadike, V. U.
    Background: Vulvovaginal candidiasis (VVC) is one of the most common infections in females. In recent decades, reports of incidence of non-albicans candida species causing VVC is increasing and this has led to a lot of therapeutic failures. Thus, this study aimed to detect Candida species among women who presented with VVC in Babcock University Teaching Hospital (BUTH), Ogun State. Methods: This was a cross-sectional retrospective hospital-based study carried out in BUTH. Candida isolates from high vaginal swab of 82 women who presented with VVC at the gynecology and family medicine clinics of the hospital were retrieved for a period of 2 years, January 2019 till December 2020. The isolates were analyzed by standard medical microbiology technique. Information on sociodemographic and behavioral factors were retrieved from clinical case notes. The data were analyzed by IBM SPSS Statistics version 26. Results: The 82 isolates analyzed yielded 87 species of Candida. Out of the 87 isolates of Candida, the albicans species were 50 (57.5%) while the non-albicans were 37 (42.5%). Among the non-albicans species, 16 (43.2%) Candida krusei had the highest frequency while 7 (19.0%) Candida tropicalis had the least and the other isolates that are unidentified by CHROMagaar accounted for 14 (37.8%). Candida albicans was predominant among 12/18 (66.7%) participants with present multiple sex partners. C. albicans was significantly associated with hormonal contraceptives and C. krusei with wearing of tight and nylon underwear, respectively, on bivariate analysis (P < 0.05) Conclusion: C. albicans was the predominant identified species from this study; however, the prevalence of the non-albicans candida species was still high
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    Emergency medical needs of Internally displaced persons.
    (Inspiration House, Osogbo, 2023) Fasola, F. A.; Omisore, B.; Oluwasola, T. O.
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    Threshold and correlation of total serum bilirubin with screening automated auditory brainstem response among newborns with hyperbilirubinemia in National Hospital Abuja.
    (2023) Oyinwola, O. I.; Muktar-Yola, M.; Olusesi, A. D.; Oluwasola, T. O.
    Objective: To determine the total serum bilirubin (TSB) cut-off value predictive of hearing impairment among newborns with hyperbilirubinemia at the National Hospital Abuja. Setting: This was a cross-sectional study conducted in the Special Care Baby Unit (SCBU) and Neonatal Intensive Care Unit (NICU) of National Hospital Abuja between August 2020 and February 2021. Methods: A universal sampling of eligible participants was done, and consent was obtained from the parent. Using the TSB and results of hearing screening carried out with the Otoport advance from Otodynamics®, the proportion of automated auditory brainstem response (AABR) screening failure was determined, and the receiver’s operating characteristics (ROC) curve coordinates were used to find the threshold bilirubin level for the risk of hearing loss. The Spearman-Rho correlation assessed the relationship between TSB level and AABR findings. Results: 160 newborns below 28 days of age, delivered at 34 weeks gestation and above, who had clinical jaundice were recruited. The prevalence of screening AABR failure in at least one ear was 26.2%. The correlation between TSB and AABR was weakly positive (rs = .189, p = .093) and the TSB cut-off for AABR failure was 16.3 mg/dl (sensitivity 45.5%, specificity 81%, Youden’s-J statistic = 0.265). Conclusion: The TSB threshold for AABR screening failure was 16.3 mg/dl, but TSB did not correlate well with screening AABR. Serum bilirubin above 15 mg/dl in late preterm and term neonates should be actively treated with phototherapy and/ or exchange blood transfusions where feasible, particularly in resource-poor settings