Browsing by Author "Oyemolade, T. A."

Now showing 1 - 2 of 2

Features and outcome of surgical management of spinal tumors in a cohort of nigerian patients
(Elsevier Inc, 2014) Adeolu, A. A.; Oyemolade, T. A.; Salami, A. A.; Adigun, T. A.; Malomo, A. O.; Akang, E. A.; Shokunbi, M. T.
OBJECTIVE: There is a dearth of information on operated cases of spinal tumors in patients in sub-Saharan Africa. The objective of this study was to evaluate the histologic pattern, anatomic distribution, and extent and outcome of surgery of Nigerian patients with spinal tumors. METHODS: This retrospective study comprised a cohort of Nigerians who underwent surgery for spinal tumors. Data obtained included patient demographics, duration of symptoms, anatomic location, imaging findings, Frankel grading before and after surgery, and type and outcome of surgery. Univariate analysis was performed, and results were compared with results from other parts of the world. RESULTS: There were 59 patients (male-to-female ratio 1:1.1) with a bimodal age distribution. The highest (20.34%) incidence was seen in the 20e29 age group. More than half (58.06%) of the patients presented with a duration of symptoms of at least 6 months (duration of symptoms was >12 months in 35.48%). Motor deficit was present in 97.73% of patients at presentation. Functional grading was Frankel A in 38.10% of patients, Frankel C in 26.19%, Frankel B in 16.67%, Frankel D in 16.67%, and Frankel E in 2.38%. The tumors were mostly in the thoracic region (65.45%), and 58% were extradural in location. Gross total tumor excision was performed in 50.88% of the cases, and subtotal resection was performed in 24.56%. Spinal stabilization was performed in 17.86% with spinous process wiring and vertical strut being the most common method of stabilization (80%) among this group. Metastasis was the most common histologic tumor type (23.21%). Meningioma accounted for 12.50% of tumors, and ependymoma, astrocytoma, and hemangioma each accounted for 7.14%. The most common source of metastasis was the prostate (38.46%). Postoperatively, 45% of patients improved neurologically, 52.5% remained the same, and 2.5% deteriorated. There was no perioperative mortality. CONCLUSIONS: Metastasis was the most common histologic type of spinal tumor in this study, and the most common location was extradural. The outcome was satisfactory in most cases with neurologic function remaining the same or improving after surgery in most patients.
Spinal meningioma: clinical profile and outcome of surgical management
(The Pan African Medical Journal, 2022) Oyemolade, T. A.; Adeolu, A. A.; Malomo, A. O.; Shokunbi, M. T.; Salami, A. A.
Spinal meningiomas are relatively rare tumors with often favorable surgical outcomes. There is a paucity of data on spinal meningiomas in the Nigerian literature. This study was designed to evaluate the incidence, anatomical distribution, and outcome of surgical treatment of spinal meningiomas at our center. This was a retrospective study of patients who underwent surgery for spinal meningioma during the study period. Data were obtained from case notes, operation, and pathology registers. Univariate analysis was performed using SPSS version 15 (SPSS Science Inc, Chicago, IL, USA). There were 11 patients in the study, all females, with an age range of 26–65 years. All patients presented with motor deficits. Four patients (36.4%) presented within six months of symptom onset, while symptom duration exceeded one year in five patients (45.5%). Preoperative functional grading was Frankel A in 2 patients (18.2%), Frankel B and C in 4 patients each (36.4%), and Frankel D in 1 patient (9.1%). Tumor locations were thoracic in six patients (54.5%), cervical in 2 patients (18.2%), and cervicothoracic in 3 patients (27.3%). All patients underwent gross total tumor resection. Postoperative neurological improvement occurred in 7 patients (63.6%), while 4 patients (36.4%) remained neurologically unchanged. Gross total tumor resection was achieved in all cases with satisfactory functional outcomes.