Scholarly works in Pharmaceutical Microbiology
Permanent URI for this collectionhttps://repository.ibadanedu.com/handle/123456789/394
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Item New triterpene isovanniloyl and antibacterial activity of constituents from the roots of Paullinia pinnata Linn (Sapindaceae)(Elsevier BV, 2014) Lasisi, A. A.; Ayinde, B. W.; Adeleye, A. O.; Onocha, P. A.; Oladosu, I. A.; Idowu, P. A.In addition to lupeyl steryl ether (1) and 3-oxo-11a-hydroxyl-20 (29) lupen (2), a new lupeol-3-isovanniloyl ester (3) was isolated from Paullinia pinnata. Using detailed 1D and 2D NMR spectra and comparison with the published data, the new compound was characterised as 3-O-isovanilloyl-3R,5R,8R,9R,10R,13R,14S,17S,18R,19R-lup-20(29)-en, for which the trivial name Paullinoyl was proposed. Compound 3 demonstrated significant antibacterial activity on the tested strains (MIC 15.2–30.20 lg/ml). The antibacterial activities obtained in this study confirmed the use of P. pinnata in traditional medicine for treating bacterial infections.Item Paullinia pinnata; Triterpene isovanniloyl; Sapindaceae; Bacterial strains(Springer Nature, 2014) Lasisi, A. A.; Ayinde, B. W.; Adeleye, A. O.; Onocha, P. A.; Oladosu, I. A.; Idowu, P. A.In addition to lupeyl steryl ether (1) and 3-oxo-11a-hydroxyl-20 (29) lupen (2), a new lupeol-3-isovanniloyl ester (3) was isolated from Paullinia pinnata. Using detailed 1D and 2D NMR spectra and comparison with the published data, the new compound was characterised as 3-O-isovanilloyl-3R,5R,8R,9R,10R,13R,14S,17S,18R,19R-lup-20(29)-en, for which the trivial name Paullinoyl was proposed. Compound 3 demonstrated significant antibacterial activity on the tested strains (MIC 15.2–30.20 lg/ml). The antibacterial activities obtained in this study confirmed the use of P. pinnata in traditional medicine for treating bacterial infections.