FACULTY OF CLINICAL SCIENCES
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Item Rural–urban differences in quality of life and associated factors among community-dwelling older persons in Oyo state, South-Western Nigeria.(Rural–urban differences in quality of life and associated factors among community-dwelling older persons in Oyo state, South-Western Nigeria., 2021) Cadmus, E. O; Adebusoye, L. A.; Owoaje, E.TAim The decline of health and functional status as a result of old age makes it necessary to assess the Quality of Life (QoL) among older persons. There is, however, limited information in this regard from low and middle-income countries such as Nigeria. This study compares the QoL and associated factors among rural and urban community-dwelling older persons (≥ 60 years) in Oyo State, Nigeria. Subject and methods A cross-sectional, comparative community-based study was carried out using an interviewer administered, semi-structured questionnaire. The QoL was determined using the World Health Organisation Quality of Life Brief Scale (WHOQOLBREF). Data were analysed using Stata version 14 at p < 0.05. Results Overall, 1,180 (588 urban and 592 rural-dwelling) respondents were interviewed. Females constituted more than half of the respondents in both communities, accounting for over two thirds (69.2%) of the population. The mean QoL scores were similar in the psychological (54.2 ± 7.4) and environmental (54.7 ± 9.5) domains. However, the mean score for the physical domain was 69.2 ± 17.0 and 74.1 ± 12 for the social domain. There was no statistically significant difference between mean scores of the QoL in the two locations except in the environmental domain (p < 0.05). Good self-rated health was a common positive predictor of higher mean scores across the four domains in both the rural and urban settings (p < 0.05). Conclusion The rural–urban differences in the mean quality of life scores in the environmental domain in the study and poorer scores in the psychological and environmental domains necessitate areas for targeted intervention and more in-depth researchItem Appraisal of the Geriatric Centre University College Hospital Ibadan.(West African College of Physicians and the West African College of Surgeons, 2021) Adebusoye, L. A.; Olowookere, O.; Ajayi, S.; Cadmus, E.O.; Labaeka, EGeriatric medicine is an emerging subspecialty in Nigeria. The interest in the care of older Nigerians followed the Madrid International Plan of Action on Ageing in April 2002. This led to an increase in research, publications and advocacy culminating in the establishment of the pioneer geriatric centre in Nigeria in 2012. Since then, there has been an increase in capacity building, manpower development and institutionalization of geriatric care in Nigeria. This is an account of the evolution of the Chief Tony Anenih Geriatric Centre, University College Hospital, Ibadan (UCH). METHODS: We undertook the review of the history, structure and key service elements in the Geriatric Centre, UCH from January 1, 2013, to December 31, 2020. RESULTS: The number of patients rose from 2,559 in the first year to 19,300 by the end of 2020. The initial four multidisciplinary units increased to 12 over the review period. Likewise, the in-patient admission increased between the first year (122 patients) and 2020 (141 patients). The overall mortality rate was 11.4% over the review period. Internship opportunities were provided to students including resident doctors, undergraduates (medical) and postgraduate students (Masters and PhD). Besides, 139 medical doctors have undergone the annual basic certificate training in geriatric medicine organised by the Centre. Also, 7 fellowship dissertations and 11 peer-reviewed papers have been published. CONCLUSION: The centre has demonstrated the possibility of caring for older patients in a low-resource setting. The employment of the multidisciplinary approach yielded a low mortality rate, higher attendance and manpower development.Item Attitude towards ageing and perceived health status of community-dwelling older persons in a low resource setting: a rural-urban comparison(BioMed Centra, 2021) Cadmus, E. O.; Adebusoye, L. A.; Owoaje, E. T.Background: Older person’s attitude to ageing is critical for their adjustment, acceptance of health-related behaviour, survival and choices. Their attitude influences how they cope with the challenges experienced while ageing, which affects their quality of life and health-related outcomes. Despite the increasing number of older persons in sub-Saharan Africa, there is limited information about their experience. This study examines the experience and attitude of older persons in Nigeria regarding the ageing process. Methods: A descriptive cross-sectional study among older persons aged 60 years and above was carried out in a selected rural and an urban community in Oyo State, south-western Nigeria. The study participants were selected using a multi-stage sampling technique. Trained research assistants collected data with the aid of an interviewer administered, semi-structured questionnaire. The Attitude to Ageing Questionnaire (AAQ) was used to measure participants’ perception of ageing in three domains (psychosocial loss, physical changes and psychological growth). Data were analysed using Stata version 14 at a level of significance p < 0.05. Results: A total of 1,180 participants (588 rural vs. 592 urban) were recruited for the study. The mean age was 73.2 ± 9.3 years. The majority (69.7 %) were females and still working (50.5 %). Overall, urban-dwelling participants had a better attitude to the ageing process in all the domains compared with rural-dwelling participants (psychological growth 32.5 ± 3.4 vs. 32.4 ± 3.3, p = 0.30; physical change 27.5 ± 5.1 vs. 26.9 ± 5.0, p = 0.03; and psychosocial loss 25.3 ± 5.7 vs. 25.0 ± 5.3, p = 0.60). Among the rural and urban-dwelling participants, good self-rated health was significantly associated with a positive attitude to ageing across the domains. Conclusions: Older persons residing in urban communities had higher positivity to ageing than their rural older counterparts. The common factor significantly associated with a positive attitude to ageing in both groups was good self-rated health. This information can be used for the planning of targeted interventions and informing policy formation for improved provisions for community-dwelling older persons in Nigeria and other sub-Saharan African countries.Item Caring for older adults during the COVID pandemic and beyond: Experience from a specialized tertiary facility for the care of older persons in a low-resource setting.(Pan African Medical Journal (PAMJ), 2020) Adebusoye, L. A.; Cadmus, E.O.; Labaeka, E. O.; Ajayi, S. A.; Olowookere, O. O.; Otegbayo, J. A.The ongoing Coronavirus disease (COVID-19) pandemic has markedly changed health care provisions and arrangements for patient care. Older adults are most susceptible to worse outcomes. The public health impact of the disease in terms of morbidity and mortality has necessitated the evolution of management protocols for effective care of older persons. This review describes our experience during this period attending to the healthcare needs of both the acutely ill and clinically stable patients at the first purpose-built facility for the care of older persons in Nigeria, the Chief Tony Anenih Geriatric Centre (CTAGC), University College Hospital, Ibadan. A major strategy recommended by the World Health Organization was a lockdown with restricted movements and laid down rules for engagement. As such, the CTAGC also embarked on steps to ensure patient safety as well as effective care. Prior to the lockdown, targeted activities included fumigation of the centre as well as health education and promotional activities. Measures were put in place to care for up to 95% of our patients at home. Thus, a “Care in Place” approach was adopted to enable them to take ownership of their care. Ambulatory older patients were seen on an out-patient basis following scheduled appointments after a telephone consultation through the hospital’s designated lines. Clients were managed for their routine health conditions which were mostly non-communicable diseases (NCDs). Also,Item Frailty and mortality among older patients in a tertiary hospital in Nigeria.(Ghana Medical Association (Accra, Ghana), 2019) Adebusoye, L. A.; Cadmus, E.O.; Owolabi, M.O.; Ogunniyi, A.Background: This study determined the frailty status and its association with mortality among older patients. Design: A prospective cohort design. Setting: Study was conducted at the medical wards of University College Hospital, Ibadan, Nigeria. Participants and study tools: Four hundred and fifty older patients (>60 years) were followed up from the day of admission to death or discharge. Information obtained includes socio demographic characteristics and clinical frailty was assessed using the Canadian Study of Health and Aging (CSHA) scale. Bivariate and multivariate analyses were carried out using SPSS version 21 at a p <0.05. Results: Overall, frailty was identified in 285 (63.3%) respondents. Mortality was significantly higher among frail respondents (25.3%) than non-frail respondents (15.4%) p=0.028. Logistic regression analysis showed factors associated with frailty were: male sex (OR=1.946 [1.005–3.774], p=0.048), non-engagement in occupational activities (OR=2.642 [1.394–5.008], p=0.003), multiple morbidities (OR=4.411 [1.944–10.006], p<0.0001), functional disability (OR=2.114 [1.029–4.343), p=0.042], malnutrition (OR=9.258 [1.029–83.301], p=0.047) and being underweight (OR=7.462 [1.499–37.037], p=0.014). Conclusion: The prevalence of frailty among medical in-hospital older patients is very high and calls for its prompt identification and management to improve their survival.Item Blueprint for health security in Nigeria by 2050: Ageing and ageing- related diseases(University of Ibadan, Nigeria, 2019) Akinyemi, R. O.; Cadmus, E. O.; Adeniji, O.; Ajayi, S.; Farombi, T.; Omobowale, O. C.; Olowookere, O. O.; Adebusoye, L. A.; Alonge, T. O.; Ogunniyi, ABackground: Nigeria is currently populated by about 200 million people of diverse ethnic, cultural and religious inclinations. Projections estimate that the proportion and absolute number of older persons aged 60 years and above (currently about 5% of the total population) will increase to 25 million by the year 2050. Ageing of the Nigerian population has far reaching multifaceted economic, psychosocial, educational and health implications. Situation analysis: In this paper, a scenario-based analysis is presented on the likely trajectory of health security for older Nigerians by the year 2050. Ageing – associated diseases are predominantly non - communicable (NCD) and their burden is likely to increase over the next 30 years. The combined burden of NCDs and infectious diseases (malaria, tuberculosis, HIV/AIDS, emerging and re – emerging diseases) suggest that the demand on health services (preventive, diagnostic, curative, rehabilitative and palliative care) from older persons and the elderly will increase in tandem with the growth of this segment of the population. Conclusion: A blueprint for achieving healthy ageing for older persons by the year 2050 is presented. This encompasses set targets, strategic plans and a monitoring and evaluation scheme. Improved funding and coverage of the National Health Insurance Scheme, better pensions and retirement benefit coverage, other social schemes and policy interventions and rigorous implementation schemes are all required for achieving health security by the year 2050 with respect to ageing and ageing – related disorders.Item Older persons’ perceptions about advanced directives and end of life issues in a geriatric care setting in southwestern Nigeria(Pan African Medical Journal (PAMJ), 2019) Cadmus, E. O.; Adebusoye, L. A.; Olowookere, O. O.; Olusegun, A. T.; Oyinlola, O.; Adeleke, R. O.; Alonge, T.O.Introduction: advanced directives enable the planning of care and support services independent of the older person’s ability to make the decision. There is a paucity of information regarding the views and preferences regarding advanced directives and other end of life issues among older persons in low and middle-income countries such as Nigeria. The study aimed to explore the knowledge, attitude and belief of older persons regarding decision making surrounding end of life and advance directives. Methods: data were collected through focus group discussions at a monthly social gathering of outpatients in a geriatric center in Oyo State, Nigeria. Discussions were audiotaped, transcribed and analyzed manually using a thematic approach. Results: respondents’ knowledge about the end of life care and advanced directives as prescribed in high income settings were sparse and did not include choices about treatment options or any medical directives. The predominant perceptions among the participants bordered mainly on the arrangements for place of death, burial and property sharing. Participants listed in order of preference the major decision makers in the advanced directive process mainly, the oldest male child, religious leaders and legal practitioners. Conclusion: our findings imply the need for improving knowledge and awareness about the benefits of advanced directives among older persons with a focus on opportunities for their active participationItem A descriptive study of the morbidity pattern of older persons presenting at a geriatric centre in southwestern Nigeria.(Wolters Kluwer - Medknow Publications, 2017) Cadmus, E. O.; Adebusoye, L. A.; Olowookere, O. O.; Oluwatosin, O. G.; Owoaje, E. T.; Alonge, T. O.Context: Rapid population ageing is a demographic reality in most countries of the world. Old age is associated with changes which may culminate in health problems, necessitating provision of appropriate preventive, curative, and rehabilitative services. However, reports from many low- and middle-income countries have shown lack of preparedness to cater for the healthcare needs of older persons. Aim: This study described the morbidity profile and its determinants among persons aged 60 years and above who presented at an established geriatric centre in southwestern Nigeria. Materials and Methods: Data were obtained from electronic health records of 4886 patients aged ≥60 years who visited the facility between 1st January 2013 and 31st December 2014. Data were analyzed using Stata version 13 (Texas, USA). Frequency distributions were used for descriptive analysis, and chi-square test was used to test associations. Results: More than a half, 2919 (59.7%), of the respondents were females and almost three quarters 3501 (71.7%) were aged between 60 and 74 years. Mean number of morbidities was 1.81 ± 0.9, and less than half, 1097 (42.0%), presented with only one morbidity, most commonly, hypertension. There were significant age-related differences for musculoskeletal (P = 0.001), endocrine (P = 0.01), and psychological problems (P = 0.01). In addition, gender differences were observed as a significantly higher proportion of females presented with general symptoms (P = 0.02) and musculoskeletal problems (P = 0.0001) than men. Conclusion: The most common presenting morbidities at this geriatric health centre were mostly no communicable diseases. Information obtained will be useful in the design of similar facilities in other parts of the country and region at large.Item The Impact of COVID-19 on older persons in Nigeria: A double jeopardy of vulnerability(Springer Nature, 2022) Cadmus, E. O.; Adebusoye, L. A.Item Predictors of weight reduction in a Nigerian family practice setting(Ghana Medical Association, 2021) Ogunbode, A. M.; Owolabi, M. O.; Ogunbode, O. O.; Adebusoye, L. A.; Ogunniyi, A.Objectives: This study identified the predictors of weight reduction among adult obese patients in a Family Practice Setting and developed a statistical model to predict weight reduction. Design: A prospective cohort design. Setting: The Family Practice Clinic, University College Hospital, Ibadan, Nigeria Participants and study tools: Obese adults were recruited into a three-month weight reduction program. Patient Information Leaflets were used for counselling, while questionnaires were administered to obtain socio-demographic and lifestyle factors. Potential predictors were assessed using the Multidimensional Scale of Perceived Social Support, Zung Depression Scale, Rosenberg Self-Esteem scale, Garner’s Eating Attitude Test-26 (EAT-26), 24-hour dietary recall and International Physical Activity Questionnaire-short form. Anthropometric indices, blood pressure and Fast-ing Lipid Profile were assessed. Descriptive and inferential statistics were used for analysis with a significance set at α0.05. Results: Most 99(76.2%) of the 130 participants achieved weight reduction and had a median weight change of -2.3kg (IQR-4, -0.5), with 66 (66.7%) out of 99 attaining the weight reduction target of 10%. The regression model showed predictors of weight reduction to be Total Cholesterol [TC] (p=0.01) and Low-Density Lipoprotein Cholesterol [LDL-C] (p=0.03). The statistical model derived for Weight reduction = 0.0028 (LDL-C) -0.029 (TC)-0.053 (EAT-26) +0.041(High-Density Lipoprotein Cholesterol). The proportion of variance of the model tested was R2 = 0.3928 (ad-justed R2 = 0.2106). Conclusion: Predictors of weight reduction among patients were eating attitude score, Total Cholesterol, Low-Density Lipid and High-Density Lipoprotein Cholesterol levels. A statistical model was developed for managing obesity among patients.