Veterinary Medicine
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Item Multidrug resistant Enterohaemorrhagic Esherichia coli serogroups in the faeces of hunted wildlife, Abeokuta, Nigeria(Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise "G. Caporale Teramo, Italy, 2022) Ojo, O. E.; Amosun, E. A.; Opebiyi, O. O.; Oyekunle, M. A.; Dipeolu, M. A.; Otesile, E. B.Wildlife plays significant roles in the dissemination and zoonotic transmission of pathogens. The enterohaemorrhagic Escherichia coli (EHEC) are associated with complicated cases of food-borne illnesses. This study investigated the presence of EHEC serogroups (026, 045, 0103, 0145, 091, 0111, 0128, 0121 and 0157) in wildlife species: cane rats (Thryonomys swinderianus), royal antelope (Neotraguspygmaeus), African giant rats (Cricetomysgambianus) and \Naterbuck(Kobusellipsiprymnus). EHEC and non-EHEC isolates from these wildlife sources were tested for susceptibility to antimicrobial agents. Overall, 127 (83.0 %) out of 153 samples yielded E. coli. Nine (5.9%) samples were positive for EHEC belonging to three serogroups as follows: 026 (n = 2), 0111 (n = 2) and 0103 (n = 5). The EHEC isolates were from cane rats (n = 6) and royal antelope (n = 3) and possessed virulence-associated genes stx, (77.8%), stx2 (100.0%), eaeA (100.0%) and hlyA (100.0%). Overall, 127 £ coli isolates showed resistance to ampicillin (99.2%), ceftiofur (90.6%), tetracycline (90.0%), cephalexin (87.4%), cefotaxime (50.4%), streptomycin 42.5%, ceftazidime (41.7%), nalidixic acid (37.0%), ciprofloxacin (43.6%), amoxicillin/davulanic acid (32.3%), gentamicin (27.6%), sulphamethoxazole/ trimethoprim (25.2%), norfloxacin (17.3%) and chloramphenicol (11.0%). The role of wildlife in the dissemination and transmission of antimicrobial resistant and zoonotic bacteria should not be neglected for effective preventive and control strategies.