FACULTY OF BASIC MEDICAL SCIENCES

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    Asymtomatic bacteriuria in antenatal patients in Ilorin, NIgeria
    (Oman Medical Specialty Board, 2012) Ajayi, A. B.; Nwabuisi, C,; Aboyeji, A. P.; Ajayi, N. S.; Fowotade, A.; Fakeye, O. O.
    Objective: To determine the prevalence of asymptomatic bacteriuria, bacteriology and sensitivity pattern in Ilorin using the gold standard of urine culture. Methods: A prospective study was carried out from 1st July to 31st October 2007, at the University of Ilorin Teaching Hospital (UITH) on 125 consenting asymptomatic pregnant women. A structured proforma was used to collect information from the women and a midstream urine specimen collected for bacteriological culture. Results: Of the 125 pregnant women, 50 had bacteriuria on urine culture giving a prevalence of 40%. The mean age of the women was 28.5 years with a standard deviation of 4.95. The age ranged between 14 and 40 years. Staphylococcus aureus was the commonest pathogen isolated (72%), followed by Proteus spp (14%). Most of the organisms showed good sensitivity to Nitrofurantoin and gentamicin. Conclusion: The prevalence of asymptomatic bacteriuria in Ilorin is high and routine urine culture is advocated for all pregnant women at booking.
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    Prevalence of measles neutralizing Antibody In Children under 15years In Southwestern Nigeria
    (Medical Microbiology and Parasitology Society of Nigeria (MMSN), 2005) Opaleye, O. O.; Adewumi, M. O.; Donbraye E,; Bakarey, A. S. .; Odaibo, G. N.; Olaleye, O. D
    The immune status of children under 15 years in the Southwestern region of Nigeria against measles virus was determined using the neutralization test with a view to assessing the herd immunity to the virus in these communities. A total of 256 serum samples collected from children were tested by the beta method of neutralization. Forty (15.6%) of these samples were found to be positive at a titre of 1:256, 35 (13.7%) at 1:128, 36(14.1%) at 1:64, 37(14.5%) at 1:32, 38 (14.8%) at 1:16, 27 (10.5%) at 1:8 and 16 (6.3%) at 1:4. Twenty-seven (10.5%) of the 256 samples had no detectable antibody to the measles virus. There was no significant relationship between the antibody titre to measles virus and the gender of the children (p > 0.05). Also, there was no significant difference using Chi square analysis between the neutralizing antibody titres and the age of the children (p > 0.05). All the children whose samples were tested were vaccinated against measles as attested to by their parents. However, the vaccination does not seem to protect all the children, for some of them had no detectable neutralizing antibody while some had low neutralizing antibody titre. In Nigeria, where only a single dose of measles vaccine is given at 9month, measles may remain a serious threat to the children population with its attendant high morbidity and mortality.